当前位置:网站首页>CAS:474922-22-0 Maleimide-PEG-DSPE Phospholipid-Polyethylene Glycol-Maleimide Brief Description
CAS:474922-22-0 Maleimide-PEG-DSPE Phospholipid-Polyethylene Glycol-Maleimide Brief Description
2022-07-31 06:14:00 【XYBMWCR】
I. Details
1. Name
Chinese: Phospholipid-Polyethylene Glycol-Maleimide (MW: 3400)
English: DSPE-PEG-MAL
Maleimide-PEG-DSPE
CAS: 474922-22-0
2. Properties
Molecular weight: 3.4k, other molecular weights can be customized (5k, 2k, 1k, etc.).Quality control at 95%+.
Physical Properties: White solid.Soluble in conventional solutions and most organic solvents.
Storage conditions: Freeze at -20°.Store away from light and dry.
Usage: For scientific research, drug release, nanotechnology and new material research, cell culture.Active compounds in the research of ligands, peptide synthesis supports, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings.
Reminder: In order to achieve the best use effect, the material should always be kept in a dry low temperature condition.Avoid frequent thawing and freezing.
Second, structural formula
Three, description
DSPE-PEG-MAL is one of the reactive phospholipid PEG reagents, which can react with sulfhydryl (thiol, -SH), DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is aA highly hydrophobic saturated 18C phospholipid.
DSPE-PEG-maleimide (DSPE-PEG-mal) is composed of DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) and maleimide groupA phospholipid-type PEG derivative.DSPE-PEG-MAL is one of the most commonly used reactive phospholipids for coupling antibodies, peptides or other ligands to the surface of liposomes and other lipid PEG nanoparticles.PEGylated phospholipids have prolonged blood circulation time and higher stability for encapsulated drugs.
Commonly used for targeted drug delivery with lipid bilayers to improve drug solubility, PEG provides stealth, prolongs circulatory half-life, reduces non-specific protein binding or cell adhesion, maleimide reacts with antibodies, suitableTargeting molecules such as ligands, proteins, peptides, etc.
Four, related products
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 20000
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 10000
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 5000
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 3400
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 2000
phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, Maleimide-PEG-DSPE, 474922-22-0, MW: 1000
Methoxy-polyethylene glycol-bismyristyl phosphatidylethanolamine, mPEG-DMPE, MW: 20000
Methoxy-polyethylene glycol-bismyristyl phosphatidylethanolamine, mPEG-DMPE, MW: 10000
Methoxy-polyethylene glycol-bismyristyl phosphatidylethanolamine, mPEG-DMPE, MW: 5000
Methoxy-polyethylene glycol-bismyristyl phosphatidylethanolamine, mPEG-DMPE, MW: 3400
Methoxy-polyethylene glycol-bismyristyl phosphatidylethanolamine, mPEG-DMPE, MW: 1000
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